Genome-wide determinants of proviral targeting, clonal abundance and expression in natural HTLV-1 infection.
The regulation of proviral latency is a central problem in retrovirology. We postulate that the genomic integration site of human T lymphotropic virus type 1 (HTLV-1) determines the pattern of expression of the provirus, which in turn determines the abundance and pathogenic potential of infected T c...
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| Main Authors: | Anat Melamed, Daniel J Laydon, Nicolas A Gillet, Yuetsu Tanaka, Graham P Taylor, Charles R M Bangham |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-03-01
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| Series: | PLoS Pathogens |
| Online Access: | https://doi.org/10.1371/journal.ppat.1003271 |
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