The ontogeny of synovial tissue macrophages

Macrophages are essential components of all body tissues, including the synovium. Tissue macrophages originate either from embryonically seeded “primitive” macrophages or from bone marrow-derived monocytes. In adults, both sources contribute to macrophage populations, with their relative proportions...

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Bibliographic Details
Main Authors: Joseph Hutton, Wenrui Sun, Tetsuo Hasegawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1603473/full
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