Molecular Mechanisms and Genome-Wide Aspects of PPAR Subtype Specific Transactivation
The peroxisome proliferator-activated receptors (PPARs) are central regulators of fat metabolism, energy homeostasis, proliferation, and inflammation. The three PPAR subtypes, PPAR𝛼, 𝛽/𝛿, and 𝛾 activate overlapping but also very different target gene programs. This review summarizes the insights int...
Saved in:
Main Authors: | Anne Bugge, Susanne Mandrup |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2010-01-01
|
Series: | PPAR Research |
Online Access: | http://dx.doi.org/10.1155/2010/169506 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The impact of glucocorticoid receptor transactivation on context-dependent cell migration dynamics
by: Szonja Polett Pósa, et al.
Published: (2025-02-01) -
Selective Modulators of PPAR-γ Activity: Molecular Aspects Related to Obesity and Side-Effects
by: Fang Zhang, et al.
Published: (2007-01-01) -
Genome-Wide and Gene-Specific Epigenomic Platforms for Hepatocellular Carcinoma Biomarker Development Trials
by: Christina Michailidi, et al.
Published: (2014-01-01) -
Identification of Taihang-chicken-specific genetic markers using genome-wide SNPs and machine learning
by: Fu Wei, et al.
Published: (2025-01-01) -
PPAR Genomics and Pharmacogenomics: Implications for Cardiovascular Disease
by: Sharon Cresci
Published: (2008-01-01)