Generation and characterisation of mice deficient in the multi-GTPase domain containing protein, GIMAP8.

Generation and characterisation of mice deficient in the multi-GTPase domain containing protein, GIMAP8.

<h4>Background</h4>GTPases of the immunity-associated protein family (GIMAPs) are predominantly expressed in mature lymphocytes. Studies of rodents deficient in GIMAP1, GIMAP4, or GIMAP5 have demonstrated that these GTPases regulate lymphocyte survival. In contrast to the other family me...

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Bibliographic Details
Main Authors: Louise M C Webb, John C Pascall, Lucy Hepburn, Christine Carter, Martin Turner, Geoffrey W Butcher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0110294
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