Monitoring circulating tumor DNA by recurrent hotspot mutations in bladder cancer

Monitoring circulating tumor DNA by recurrent hotspot mutations in bladder cancer

Abstract Background Liquid biopsy can evaluate minimally residual disease. Hotspot mutations are also common in non-coding regions among the MIBC patients. We evaluated the status of MIBC with hotspot mutations with cfDNA. Methods Tumor and blood from MIBC patients were collected prospectively. We e...

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Main Authors: Shigehiro Tsukahara, Masaki Shiota, Takashi Matsumoto, Dai Takamatsu, Shohei Nagakawa, Nozomi Noda, Shinya Matsumoto, Mikako Yagi, Takeshi Uchiumi, Yuya Kunisaki, Dongchon Kang, Masatoshi Eto
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:BJC Reports
Online Access:https://doi.org/10.1038/s44276-025-00143-4
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https://doi.org/10.1038/s44276-025-00143-4

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