Deciphering the dark cancer phosphoproteome using machine-learned co-regulation of phosphosites
Abstract Mass spectrometry-based phosphoproteomics offers a comprehensive view of protein phosphorylation, yet our limited knowledge about the regulation and function of most phosphosites hampers the extraction of meaningful biological insights. To address this challenge, we integrate machine learni...
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| Main Authors: | Wen Jiang, Eric J. Jaehnig, Yuxing Liao, Zhiao Shi, Tomer M. Yaron-Barir, Jared L. Johnson, Lewis C. Cantley, Bing Zhang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-57993-2 |
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