Striking Cardioprotective Effects of an Adiponectin Receptor Agonist in an Aged Mouse Model of Duchenne Muscular Dystrophy

Striking Cardioprotective Effects of an Adiponectin Receptor Agonist in an Aged Mouse Model of Duchenne Muscular Dystrophy

Adiponectin (ApN) is a hormone with potent effects on various tissues. We previously demonstrated its ability to counteract Duchenne muscular dystrophy (DMD), a severe muscle disorder. However, its therapeutic use is limited. AdipoRon, an orally active ApN mimic, offers a promising alternative. Whil...

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Bibliographic Details
Main Authors: Michel Abou-Samra, Nicolas Dubuisson, Alice Marino, Camille M. Selvais, Versele Romain, Maria A. Davis-López de Carrizosa, Laurence Noel, Christophe Beauloye, Sonia M. Brichard, Sandrine Horman
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Antioxidants
Subjects:
adiponectin
Duchenne muscular dystrophy
cardiomyopathy
inflammation
fibrosis
mitochondria
Online Access:https://www.mdpi.com/2076-3921/13/12/1551
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