HSP105 inhibition downregulates store-operated calcium entry and promotes acute UVB-induced tight junction disruption.

<h4>Background</h4>Tight junction abnormalities are a common feature of inflammatory skin diseases such as psoriasis and atopic dermatitis and contribute to systemic immune responses. Evidence provided to date suggests that Heat shock protein 105 kDa (HSP105) exhibits significant protect...

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Bibliographic Details
Main Authors: Kaiyi Zhou, Siyu Luo, Qinxiao Wang, Qian Ye, Sheng Fang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0314816&type=printable
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