Prognostic and Therapeutic Implications of Alamandine Receptor MrgD Expression in Clear Cell Renal Cell Carcinoma with Development of Metastatic Disease

Prognostic and Therapeutic Implications of Alamandine Receptor MrgD Expression in Clear Cell Renal Cell Carcinoma with Development of Metastatic Disease

Despite advances in the management of advanced clear cell renal cell carcinoma (ccRCC), robust biomarkers for prognosis and therapeutic response prediction remain elusive. Dysregulation of the intrarenal renin–angiotensin system (RAS) has been implicated in renal carcinogenesis but little explored,...

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Main Authors: Gorka Larrinaga, Jon Danel Solano-Iturri, Inés Arrieta-Aguirre, Asier Valdivia, David Lecumberri, Ane Miren Iturregui, Charles H. Lawrie, María Armesto, Juan F. Dorado, Caroline E. Nunes-Xavier, Rafael Pulido, José I. López, Javier C. Angulo
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Biomolecules
Subjects:
clear cell renal cell carcinoma
metastatic
prognostic
tyrosin kinase inhibitors
biomarker
renin–angiotensin system
Online Access:https://www.mdpi.com/2218-273X/15/3/387
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