Antibody-drug conjugates for treating early-stage breast cancer: current use, anticipated evolutions

Abstract Antibody-drug conjugates (ADCs) combine the specificity of monoclonal antibodies with potent cytotoxic payloads, leading to improved tumor delivery of the latter. After improving outcomes for patients with metastatic disease, ADC testing moved to the curative setting, where already one agen...

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Bibliographic Details
Main Authors: Pooja Patel, Antonio Giordano, Sara Giordano, Ilana Schlam, Sara M. Tolaney, Paolo Tarantino
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-025-00800-4
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