Stem Cell Therapy for Diseases of Livestock Animals: An In-Depth Review
Stem cells are unique, undifferentiated cells that have the ability to both replicate themselves and develop into specialized cell types. This dual capability makes them valuable in the development of regenerative medicine. Current development in stem cell research has widened their application in c...
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| Language: | English |
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MDPI AG
2025-01-01
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| Series: | Veterinary Sciences |
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| Online Access: | https://www.mdpi.com/2306-7381/12/1/67 |
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| author | Raghavendra B. Narasimha Singireddy Shreya Vijay Anand Jayabal Vikas Yadav Prasana Kumar Rath Bidyut Prava Mishra Sudhakar Kancharla Prachetha Kolli Gowtham Mandadapu Sudarshan Kumar Ashok Kumar Mohanty Manoj Kumar Jena |
| author_facet | Raghavendra B. Narasimha Singireddy Shreya Vijay Anand Jayabal Vikas Yadav Prasana Kumar Rath Bidyut Prava Mishra Sudhakar Kancharla Prachetha Kolli Gowtham Mandadapu Sudarshan Kumar Ashok Kumar Mohanty Manoj Kumar Jena |
| author_sort | Raghavendra B. Narasimha |
| collection | DOAJ |
| description | Stem cells are unique, undifferentiated cells that have the ability to both replicate themselves and develop into specialized cell types. This dual capability makes them valuable in the development of regenerative medicine. Current development in stem cell research has widened their application in cell therapy, drug discovery, reproductive cloning in animals, and cell models for various diseases. Although there are substantial studies revealing the treatment of human degenerative diseases using stem cells, this is yet to be explored in livestock animals. Many diseases in livestock species such as mastitis, laminitis, neuromuscular disorders, autoimmune diseases, and some debilitating diseases are not covered completely by the existing drugs and treatment can be improved by using different types of stem cells like embryonic stem cells, adult stem cells, and induced pluripotent stem cells. This review mainly focuses on the use of stem cells for disease treatment in livestock animals. In addition to the diseases mentioned, the potential of stem cells can be helpful in wound healing, skin disease therapy, and treatment of some genetic disorders. This article explores the potential of stem cells from various sources in the therapy of livestock diseases and also their role in the conservation of endangered species as well as disease model preparation. Moreover, the future perspectives and challenges associated with the application of stem cells in livestock are discussed. Overall, the transformative impact of stem cell research on the livestock sector is comprehensively studied which will help researchers to design future research work on stem cells related to livestock diseases. |
| format | Article |
| id | doaj-art-b355f40a735447f1b3b6b48100cfd553 |
| institution | Kabale University |
| issn | 2306-7381 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Veterinary Sciences |
| spelling | doaj-art-b355f40a735447f1b3b6b48100cfd5532025-01-24T13:52:10ZengMDPI AGVeterinary Sciences2306-73812025-01-011216710.3390/vetsci12010067Stem Cell Therapy for Diseases of Livestock Animals: An In-Depth ReviewRaghavendra B. Narasimha0Singireddy Shreya1Vijay Anand Jayabal2Vikas Yadav3Prasana Kumar Rath4Bidyut Prava Mishra5Sudhakar Kancharla6Prachetha Kolli7Gowtham Mandadapu8Sudarshan Kumar9Ashok Kumar Mohanty10Manoj Kumar Jena11Department of Biotechnology, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara 144411, Punjab, IndiaDepartment of Biotechnology, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara 144411, Punjab, IndiaDepartment of Animal Biotechnology, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Chennai 600051, Tamil Nadu, IndiaDepartment of Clinical Sciences, Clinical Research Centre, Skåne University Hospital, Lund University, SE 20213 Malmö, SwedenCollege of Veterinary Science and AH, Odisha University of Agriculture and Technology, Bhubaneswar 751003, Odisha, IndiaCollege of Veterinary Science and AH, Odisha University of Agriculture and Technology, Bhubaneswar 751003, Odisha, IndiaDevansh Lab Werks, 234 Aquarius Drive, Homewood, AL 35209, USAMicrogen Health Inc., 14225 Sullyfield Cir Suite E, Chantilly, VA 20151, USADevansh Lab Werks, 234 Aquarius Drive, Homewood, AL 35209, USACell, Molecular and Proteomics Lab, Animal Biotechnology Centre, ICAR-National Dairy Research Institute (ICAR-NDRI), Karnal 132001, Haryana, IndiaICAR-Central Institute for Research on Cattle (ICAR-CIRC), Meerut 250001, Uttar Pradesh, IndiaDepartment of Biotechnology, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara 144411, Punjab, IndiaStem cells are unique, undifferentiated cells that have the ability to both replicate themselves and develop into specialized cell types. This dual capability makes them valuable in the development of regenerative medicine. Current development in stem cell research has widened their application in cell therapy, drug discovery, reproductive cloning in animals, and cell models for various diseases. Although there are substantial studies revealing the treatment of human degenerative diseases using stem cells, this is yet to be explored in livestock animals. Many diseases in livestock species such as mastitis, laminitis, neuromuscular disorders, autoimmune diseases, and some debilitating diseases are not covered completely by the existing drugs and treatment can be improved by using different types of stem cells like embryonic stem cells, adult stem cells, and induced pluripotent stem cells. This review mainly focuses on the use of stem cells for disease treatment in livestock animals. In addition to the diseases mentioned, the potential of stem cells can be helpful in wound healing, skin disease therapy, and treatment of some genetic disorders. This article explores the potential of stem cells from various sources in the therapy of livestock diseases and also their role in the conservation of endangered species as well as disease model preparation. Moreover, the future perspectives and challenges associated with the application of stem cells in livestock are discussed. Overall, the transformative impact of stem cell research on the livestock sector is comprehensively studied which will help researchers to design future research work on stem cells related to livestock diseases.https://www.mdpi.com/2306-7381/12/1/67stem cell therapymesenchymal stem cellsdisease modelspluripotencylivestock |
| spellingShingle | Raghavendra B. Narasimha Singireddy Shreya Vijay Anand Jayabal Vikas Yadav Prasana Kumar Rath Bidyut Prava Mishra Sudhakar Kancharla Prachetha Kolli Gowtham Mandadapu Sudarshan Kumar Ashok Kumar Mohanty Manoj Kumar Jena Stem Cell Therapy for Diseases of Livestock Animals: An In-Depth Review Veterinary Sciences stem cell therapy mesenchymal stem cells disease models pluripotency livestock |
| title | Stem Cell Therapy for Diseases of Livestock Animals: An In-Depth Review |
| title_full | Stem Cell Therapy for Diseases of Livestock Animals: An In-Depth Review |
| title_fullStr | Stem Cell Therapy for Diseases of Livestock Animals: An In-Depth Review |
| title_full_unstemmed | Stem Cell Therapy for Diseases of Livestock Animals: An In-Depth Review |
| title_short | Stem Cell Therapy for Diseases of Livestock Animals: An In-Depth Review |
| title_sort | stem cell therapy for diseases of livestock animals an in depth review |
| topic | stem cell therapy mesenchymal stem cells disease models pluripotency livestock |
| url | https://www.mdpi.com/2306-7381/12/1/67 |
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