Fatigue and associated factors in multiple sclerosis patients in Latvia
Background and objectives. Fatigue is one of the most common symptoms of multiple sclerosis (MS). The aim of this study was to determine the presence of fatigue in MS patients in Latvia and its relation to life style factors, neurological disability and depression. Material and methods. This cross-...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Vilnius University Press
2018-03-01
|
| Series: | Neurologijos seminarai |
| Subjects: | |
| Online Access: | https://www.journals.vu.lt/neurologijos_seminarai/article/view/27851 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832593081332924416 |
|---|---|
| author | S. Šetlere A. Abelsen D. Pastare A. Millers |
| author_facet | S. Šetlere A. Abelsen D. Pastare A. Millers |
| author_sort | S. Šetlere |
| collection | DOAJ |
| description |
Background and objectives. Fatigue is one of the most common symptoms of multiple sclerosis (MS). The aim of this study was to determine the presence of fatigue in MS patients in Latvia and its relation to life style factors, neurological disability and depression.
Material and methods. This cross-sectional study included 117 participants (44 patients with MS and 73 healthy control group). Applied research instruments were: Expanded Disability Status Scale (EDSS), Patient Health Questionnaire (PHQ-9), Fatigue Severity Scale (FSS), and the general questionnaire for the collection of socio-demographic, life style habits and clinical data constructed for the purposes of this study.
Results. Mean FSS score was 3.9±1.9 in MS group. 26 (59.1%) patients had FSS score of 3.8 or more and were classified as a fatigue group (MSF) while 18 (40.9%) patients had FSS of 3.7 or less and were classified as a non-fatigue (MSNF) group. There was statistically significant difference between MSF and MSNF groups considering PHQ-9 score (p=0.019), FSS score (p<0.001) and EDSS score (p<0.001). Significant correlations of fatigue with depression (r=0.48, p=0.001), fatigue with neurological disability (r=0.49, p=0.001) and fatigue with smoking (r=0.29, p=0.054) were confirmed.
Conclusions. Fatigue is a common symptom in MS patients in Latvia. This study supports significant association between fatigue and clinical factors (disability, depression) and modifiable lifestyle factor – smoking.
|
| format | Article |
| id | doaj-art-b316722048be4d7ab5ac7b97c2982e44 |
| institution | Kabale University |
| issn | 1392-3064 2424-5917 |
| language | English |
| publishDate | 2018-03-01 |
| publisher | Vilnius University Press |
| record_format | Article |
| series | Neurologijos seminarai |
| spelling | doaj-art-b316722048be4d7ab5ac7b97c2982e442025-01-20T18:23:19ZengVilnius University PressNeurologijos seminarai1392-30642424-59172018-03-01221(75)10.29014/ns.2018.05Fatigue and associated factors in multiple sclerosis patients in LatviaS. Šetlere 0A. Abelsen 1D. Pastare 2A. Millers 3Riga Stradins University, LatviaRiga Stradins University, LatviaRiga Stradins University, LatviaRiga Stradins University, Latvia Background and objectives. Fatigue is one of the most common symptoms of multiple sclerosis (MS). The aim of this study was to determine the presence of fatigue in MS patients in Latvia and its relation to life style factors, neurological disability and depression. Material and methods. This cross-sectional study included 117 participants (44 patients with MS and 73 healthy control group). Applied research instruments were: Expanded Disability Status Scale (EDSS), Patient Health Questionnaire (PHQ-9), Fatigue Severity Scale (FSS), and the general questionnaire for the collection of socio-demographic, life style habits and clinical data constructed for the purposes of this study. Results. Mean FSS score was 3.9±1.9 in MS group. 26 (59.1%) patients had FSS score of 3.8 or more and were classified as a fatigue group (MSF) while 18 (40.9%) patients had FSS of 3.7 or less and were classified as a non-fatigue (MSNF) group. There was statistically significant difference between MSF and MSNF groups considering PHQ-9 score (p=0.019), FSS score (p<0.001) and EDSS score (p<0.001). Significant correlations of fatigue with depression (r=0.48, p=0.001), fatigue with neurological disability (r=0.49, p=0.001) and fatigue with smoking (r=0.29, p=0.054) were confirmed. Conclusions. Fatigue is a common symptom in MS patients in Latvia. This study supports significant association between fatigue and clinical factors (disability, depression) and modifiable lifestyle factor – smoking. https://www.journals.vu.lt/neurologijos_seminarai/article/view/27851multiple sclerosisfatiguedepression |
| spellingShingle | S. Šetlere A. Abelsen D. Pastare A. Millers Fatigue and associated factors in multiple sclerosis patients in Latvia Neurologijos seminarai multiple sclerosis fatigue depression |
| title | Fatigue and associated factors in multiple sclerosis patients in Latvia |
| title_full | Fatigue and associated factors in multiple sclerosis patients in Latvia |
| title_fullStr | Fatigue and associated factors in multiple sclerosis patients in Latvia |
| title_full_unstemmed | Fatigue and associated factors in multiple sclerosis patients in Latvia |
| title_short | Fatigue and associated factors in multiple sclerosis patients in Latvia |
| title_sort | fatigue and associated factors in multiple sclerosis patients in latvia |
| topic | multiple sclerosis fatigue depression |
| url | https://www.journals.vu.lt/neurologijos_seminarai/article/view/27851 |
| work_keys_str_mv | AT ssetlere fatigueandassociatedfactorsinmultiplesclerosispatientsinlatvia AT aabelsen fatigueandassociatedfactorsinmultiplesclerosispatientsinlatvia AT dpastare fatigueandassociatedfactorsinmultiplesclerosispatientsinlatvia AT amillers fatigueandassociatedfactorsinmultiplesclerosispatientsinlatvia |