The global transcriptional regulator MgaSpn affects the virulence of Streptococcus pneumoniae by regulating PcpA

Abstract The global transcriptional regulator MgaSpn is a significant virulence factor of Streptococcus pneumoniae. In our previous study, we found that MgaSpn is a regulator of bacterial virulence by modulating the levels of phosphorylcholine (ChoP) and capsular polysaccharides (CPS) on the surface...

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Bibliographic Details
Main Authors: Shuhui Wang, Tianyi Xu, Ye Tao, Li Lei, Xuemei Zhang, Yibing Yin, Yuqiang Zheng
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Microbiology
Subjects:
Online Access:https://doi.org/10.1186/s12866-025-04047-8
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