Effects of PDE4 inhibitors on lipopolysaccharide-induced priming of superoxide anion production from human mononuclear cells

Aims: Phosphodiesterase 4 (PDE4) inhibitors have been described as potent anti-inflammatory compounds, involving an increase in intracellular levels of cyclic 3',5'-adenosine monophosphate (AMP). The aim of this study was to compare the effects of selective PDE4 inhibitors, rolipram and RP...

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Bibliographic Details
Main Authors: Noëlla Germain, Marianne Corbel, Chantal Belleguic, Elisabeth Boichot, Vincent Lagente
Format: Article
Language:English
Published: Wiley 2001-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/09629350123856
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