Vascular endothelial growth factor-receptor 1 inhibition aggravates diabetic nephropathy through eNOS signaling pathway in db/db mice.

Vascular endothelial growth factor-receptor 1 inhibition aggravates diabetic nephropathy through eNOS signaling pathway in db/db mice.

The manipulation of vascular endothelial growth factor (VEGF)-receptors (VEGFRs) in diabetic nephropathy is as controversial as issue as ever. It is known to be VEGF-A and VEGFR2 that regulate most of the cellular actions of VEGF in experimental diabetic nephropathy. On the other hand, such factors...

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Main Authors: Keun Suk Yang, Ji Hee Lim, Tae Woo Kim, Min Young Kim, Yaeni Kim, Sungjin Chung, Seok Joon Shin, Beom Soon Choi, Hyung Wook Kim, Yong-Soo Kim, Yoon Sik Chang, Hye Won Kim, Cheol Whee Park
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094540&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094540&type=printable

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