Oncocytic papillary renal cell carcinoma (OPRCC): 2 case report and literature review

Oncocytic papillary renal cell carcinoma (OPRCC) is a new papillary renal cell carcinoma (OPRCC) added to the 2016 WHO Classification of Tumors of the Urinary and Male Reproductive System. It is a subtype of carcinoma, PRCC, which is very rare and it is very characteristic and interesting. The morph...

Full description

Saved in:
Bibliographic Details
Main Authors: Yanchen Wang, Lihui Guan, Yaming Liu, Yuxuan Liu, Xiaoyan Guo, Yaofei Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1541692/full
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832576568142069760
author Yanchen Wang
Yanchen Wang
Lihui Guan
Lihui Guan
Yaming Liu
Yuxuan Liu
Xiaoyan Guo
Yaofei Sun
Yaofei Sun
author_facet Yanchen Wang
Yanchen Wang
Lihui Guan
Lihui Guan
Yaming Liu
Yuxuan Liu
Xiaoyan Guo
Yaofei Sun
Yaofei Sun
author_sort Yanchen Wang
collection DOAJ
description Oncocytic papillary renal cell carcinoma (OPRCC) is a new papillary renal cell carcinoma (OPRCC) added to the 2016 WHO Classification of Tumors of the Urinary and Male Reproductive System. It is a subtype of carcinoma, PRCC, which is very rare and it is very characteristic and interesting. The morphology, immunophenotype, genetic characteristics and prognosis of OPRCC are uncertain, so the diagnosis and post-operative management of OPRCC are challenging. Recently, two patients with OPRCC have been treated in our hospital, both of whom have undergone surgical treatment. The information of these two cases is described as follows, and the literature is further reviewed to share the current diagnosis and treatment characteristics of OPRCC and the research progress after surgery. At the same time, the diagnosis of OPRCC disease is subdivided from PRCC disease, and the diagnosis of OPRCC disease is more precise. To optimize the individualized management of patients with renal cell carcinoma in order to improve the understanding and diagnosis of the disease.
format Article
id doaj-art-b28d3123041e4c49a6d2b5accf506e07
institution Kabale University
issn 2234-943X
language English
publishDate 2025-01-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Oncology
spelling doaj-art-b28d3123041e4c49a6d2b5accf506e072025-01-31T05:10:26ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-01-011410.3389/fonc.2024.15416921541692Oncocytic papillary renal cell carcinoma (OPRCC): 2 case report and literature reviewYanchen Wang0Yanchen Wang1Lihui Guan2Lihui Guan3Yaming Liu4Yuxuan Liu5Xiaoyan Guo6Yaofei Sun7Yaofei Sun8Department of Urology, Weifang People’s Hospital, Shandong Second Medical University, Weifang, Shandong, ChinaShandong Provincial Key Laboratory for Prevention and Treatment of Urological Diseases in Medicine and Health, Weifang, Shandong, ChinaDepartment of Urology, Weifang People’s Hospital, Shandong Second Medical University, Weifang, Shandong, ChinaShandong Provincial Key Laboratory for Prevention and Treatment of Urological Diseases in Medicine and Health, Weifang, Shandong, ChinaDepartment of Urology, Yidu Central Hospital of Weifang City, Weifang, Shandong, ChinaSchool of Clinical Medicine, Shandong Second Medical University, Weifang, ChinaDepartment of Nuclear Medicine, Weifang People’s Hospital, Shandong Second Medical University, Weifang, Shandong, ChinaDepartment of Urology, Weifang People’s Hospital, Shandong Second Medical University, Weifang, Shandong, ChinaShandong Provincial Key Laboratory for Prevention and Treatment of Urological Diseases in Medicine and Health, Weifang, Shandong, ChinaOncocytic papillary renal cell carcinoma (OPRCC) is a new papillary renal cell carcinoma (OPRCC) added to the 2016 WHO Classification of Tumors of the Urinary and Male Reproductive System. It is a subtype of carcinoma, PRCC, which is very rare and it is very characteristic and interesting. The morphology, immunophenotype, genetic characteristics and prognosis of OPRCC are uncertain, so the diagnosis and post-operative management of OPRCC are challenging. Recently, two patients with OPRCC have been treated in our hospital, both of whom have undergone surgical treatment. The information of these two cases is described as follows, and the literature is further reviewed to share the current diagnosis and treatment characteristics of OPRCC and the research progress after surgery. At the same time, the diagnosis of OPRCC disease is subdivided from PRCC disease, and the diagnosis of OPRCC disease is more precise. To optimize the individualized management of patients with renal cell carcinoma in order to improve the understanding and diagnosis of the disease.https://www.frontiersin.org/articles/10.3389/fonc.2024.1541692/fullPRCCOPRCCimmunohistochemistrygenetic pathological featurestargeted immune drugs
spellingShingle Yanchen Wang
Yanchen Wang
Lihui Guan
Lihui Guan
Yaming Liu
Yuxuan Liu
Xiaoyan Guo
Yaofei Sun
Yaofei Sun
Oncocytic papillary renal cell carcinoma (OPRCC): 2 case report and literature review
Frontiers in Oncology
PRCC
OPRCC
immunohistochemistry
genetic pathological features
targeted immune drugs
title Oncocytic papillary renal cell carcinoma (OPRCC): 2 case report and literature review
title_full Oncocytic papillary renal cell carcinoma (OPRCC): 2 case report and literature review
title_fullStr Oncocytic papillary renal cell carcinoma (OPRCC): 2 case report and literature review
title_full_unstemmed Oncocytic papillary renal cell carcinoma (OPRCC): 2 case report and literature review
title_short Oncocytic papillary renal cell carcinoma (OPRCC): 2 case report and literature review
title_sort oncocytic papillary renal cell carcinoma oprcc 2 case report and literature review
topic PRCC
OPRCC
immunohistochemistry
genetic pathological features
targeted immune drugs
url https://www.frontiersin.org/articles/10.3389/fonc.2024.1541692/full
work_keys_str_mv AT yanchenwang oncocyticpapillaryrenalcellcarcinomaoprcc2casereportandliteraturereview
AT yanchenwang oncocyticpapillaryrenalcellcarcinomaoprcc2casereportandliteraturereview
AT lihuiguan oncocyticpapillaryrenalcellcarcinomaoprcc2casereportandliteraturereview
AT lihuiguan oncocyticpapillaryrenalcellcarcinomaoprcc2casereportandliteraturereview
AT yamingliu oncocyticpapillaryrenalcellcarcinomaoprcc2casereportandliteraturereview
AT yuxuanliu oncocyticpapillaryrenalcellcarcinomaoprcc2casereportandliteraturereview
AT xiaoyanguo oncocyticpapillaryrenalcellcarcinomaoprcc2casereportandliteraturereview
AT yaofeisun oncocyticpapillaryrenalcellcarcinomaoprcc2casereportandliteraturereview
AT yaofeisun oncocyticpapillaryrenalcellcarcinomaoprcc2casereportandliteraturereview