A 15-Item modification of the PSP rating scale to improve clinical meaningfulness and statistical performance

Abstract Progressive supranuclear palsy (PSP) is a rare neurodegenerative disorder characterized by physical, cognitive, and behavioral impairments. The PSP Rating Scale (PSPRS) is a widely used and validated, clinical scale to monitor disease progression. Here we show the modification of PSPRS to i...

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Bibliographic Details
Main Authors: Tien Dam, Lili Yang, Colin Gillis, Yumeng Li, John O’Gorman, Barbara Kolb, Adam L. Boxer, Lawrence Golbe, Samantha Budd Haeberlein, On behalf of the AL-108-231, PROSPERA, and 4RTNI investigators
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55442-0
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