Human Neutrophil Defensins Disrupt Liver Interendothelial Junctions and Aggravate Sepsis
Human neutrophil peptides 1-3 (HNP1-3), also known as human α-defensins, are the most abundant neutrophil granule proteins. The genes that encode HNP1-3, DEFA1/DEFA3, exhibit extensive copy number variations, which correlate well with their protein levels. Human and mouse studies have shown that inc...
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Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2022/7659282 |
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