Modulatory effects of rutin on the expression of cytochrome P450s and antioxidant enzymes in human hepatoma cells
Expression of a drug and xenobiotic metabolizing enzymes, cytochrome P450s (CYPs), and antioxidant enzymes can be modulated by various factors. The flavonoid rutin was investigated for its anti-carcinogen and protective effects as well as modulatory action on CYPs and phase II enzymes in human hepat...
Saved in:
Main Author: | Karakurt Sedar |
---|---|
Format: | Article |
Language: | English |
Published: |
Sciendo
2016-12-01
|
Series: | Acta Pharmaceutica |
Subjects: | |
Online Access: | https://doi.org/10.1515/acph-2016-0046 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Screening of flavonoid aglycons’ metabolism mediated by the human liver cytochromes P450
by: Benković Goran, et al.
Published: (2019-12-01) -
The tyrosine kinase inhibitor lenvatinib is oxidized by rat cytochromes P450 and affects their expression in rat liver
by: Indra Radek, et al.
Published: (2024-09-01) -
Novel (Q)SAR models for prediction of reversible and time-dependent inhibition of cytochrome P450 enzymes
by: Sadegh Faramarzi, et al.
Published: (2025-02-01) -
Overexpression of multiple cytochrome P450 genes with and without knockdown resistance mutations confers high resistance to deltamethrin in Culex quinquefasciatus
by: Saowanee Chamnanya, et al.
Published: (2025-01-01) -
Continuous Consumption of Reused Palm Oil Induced Hepatic Injury, Depletion of Glutathione Stores, and Modulation of Cytochrome P450 Profiles in Mice
by: Waranya Chatuphonprasert, et al.
Published: (2019-01-01)