Non-invasive electron paramagnetic resonance imaging detects tumor redox imbalance induced by ferroptosis

Non-invasive electron paramagnetic resonance imaging detects tumor redox imbalance induced by ferroptosis

Targeting ferroptosis, cell death caused by the iron-dependent accumulation of lipid peroxides, and disruption of the redox balance are promising strategies in cancer therapy owing to the physiological characteristics of cancer cells. However, the detection of ferroptosis using in vivo imaging remai...

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Bibliographic Details
Main Authors: Kazuhiro Kato, Hironobu Yasui, Hideo Sato-Akaba, Miho C. Emoto, Hirotada G. Fujii, Maciej M. Kmiec, Periannan Kuppusamy, Masaki Nagane, Tadashi Yamashita, Osamu Inanami
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Redox Report
Subjects:
Electron paramagnetic resonance imaging
Redox imaging‌
tumor redox status
ferroptosis
cancer therapy
‌Imidazole ketone erastin
Online Access:https://www.tandfonline.com/doi/10.1080/13510002.2025.2454887
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https://www.tandfonline.com/doi/10.1080/13510002.2025.2454887

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