Antibacterial and Antibiofilm Activities of Cinnamomum Sp. Essential Oil and Cinnamaldehyde: Antimicrobial Activities
To assess the activities of essential oils derived from the trunk bark of Cinnamomum zeylanicum (EOCz) and Cinnamomum cassia (EOCc) as well as cinnamaldehyde on bacterial biofilms of clinical interest. Antimicrobial activity was assessed by the broth microdilution method to determine minimum inhibit...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2018/7405736 |
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| author | Diego F. Firmino Theodora T. A. Cavalcante Geovany A. Gomes Nairley C. S. Firmino Lucas D. Rosa Mário G. de Carvalho Francisco E. A. Catunda Jr |
| author_facet | Diego F. Firmino Theodora T. A. Cavalcante Geovany A. Gomes Nairley C. S. Firmino Lucas D. Rosa Mário G. de Carvalho Francisco E. A. Catunda Jr |
| author_sort | Diego F. Firmino |
| collection | DOAJ |
| description | To assess the activities of essential oils derived from the trunk bark of Cinnamomum zeylanicum (EOCz) and Cinnamomum cassia (EOCc) as well as cinnamaldehyde on bacterial biofilms of clinical interest. Antimicrobial activity was assessed by the broth microdilution method to determine minimum inhibitory concentrations (MICs). Antibiofilm activity was assessed by quantifying the biomass and determining the number of viable cells. The chemical composition of the essential oils was determined. The results showed that the major component of EOCz and EOCc was cinnamaldehyde. For the assayed substances, biofilm biomasses were reduced by up to 99.9%, and Streptococcus pyogenes, Pseudomonas aeruginosa, and Escherichia coli biofilms were sensitive to all of the concentrations and substances analysed. In cell viability tests, 2 mg/ml of cinnamaldehyde reduced the number of viable cells by 5.74 Log CFU/ml. EOCz, EOCc, and cinnamaldehyde exhibited antimicrobial and antibiofilm activities. This work describes substances with potential use against infections caused by bacterial biofilms. |
| format | Article |
| id | doaj-art-b138e60731dc4bc192df41d0cf24d1a6 |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-b138e60731dc4bc192df41d0cf24d1a62025-02-03T06:08:16ZengWileyThe Scientific World Journal2356-61401537-744X2018-01-01201810.1155/2018/74057367405736Antibacterial and Antibiofilm Activities of Cinnamomum Sp. Essential Oil and Cinnamaldehyde: Antimicrobial ActivitiesDiego F. Firmino0Theodora T. A. Cavalcante1Geovany A. Gomes2Nairley C. S. Firmino3Lucas D. Rosa4Mário G. de Carvalho5Francisco E. A. Catunda Jr6University Center UNINTA, Exact Sciences Center, Sobral, CE, BrazilUniversity Center UNINTA, Medical Sciences Center, Sobral, CE, BrazilAcarau Valley State University, Center for Science and Technology, Sobral, CE, BrazilUniversity Center UNINTA, Health Sciences Center, Sobral, CE, BrazilUniversity Center UNINTA, Health Sciences Center, Sobral, CE, BrazilFederal Rural University of Rio de Janeiro, Exact Sciences Center, Seropédica, RJ, BrazilState University of the Tocantina Region of Maranhão, Center for Exact, Natural and Technological Sciences, Imperatriz, MA, BrazilTo assess the activities of essential oils derived from the trunk bark of Cinnamomum zeylanicum (EOCz) and Cinnamomum cassia (EOCc) as well as cinnamaldehyde on bacterial biofilms of clinical interest. Antimicrobial activity was assessed by the broth microdilution method to determine minimum inhibitory concentrations (MICs). Antibiofilm activity was assessed by quantifying the biomass and determining the number of viable cells. The chemical composition of the essential oils was determined. The results showed that the major component of EOCz and EOCc was cinnamaldehyde. For the assayed substances, biofilm biomasses were reduced by up to 99.9%, and Streptococcus pyogenes, Pseudomonas aeruginosa, and Escherichia coli biofilms were sensitive to all of the concentrations and substances analysed. In cell viability tests, 2 mg/ml of cinnamaldehyde reduced the number of viable cells by 5.74 Log CFU/ml. EOCz, EOCc, and cinnamaldehyde exhibited antimicrobial and antibiofilm activities. This work describes substances with potential use against infections caused by bacterial biofilms.http://dx.doi.org/10.1155/2018/7405736 |
| spellingShingle | Diego F. Firmino Theodora T. A. Cavalcante Geovany A. Gomes Nairley C. S. Firmino Lucas D. Rosa Mário G. de Carvalho Francisco E. A. Catunda Jr Antibacterial and Antibiofilm Activities of Cinnamomum Sp. Essential Oil and Cinnamaldehyde: Antimicrobial Activities The Scientific World Journal |
| title | Antibacterial and Antibiofilm Activities of Cinnamomum Sp. Essential Oil and Cinnamaldehyde: Antimicrobial Activities |
| title_full | Antibacterial and Antibiofilm Activities of Cinnamomum Sp. Essential Oil and Cinnamaldehyde: Antimicrobial Activities |
| title_fullStr | Antibacterial and Antibiofilm Activities of Cinnamomum Sp. Essential Oil and Cinnamaldehyde: Antimicrobial Activities |
| title_full_unstemmed | Antibacterial and Antibiofilm Activities of Cinnamomum Sp. Essential Oil and Cinnamaldehyde: Antimicrobial Activities |
| title_short | Antibacterial and Antibiofilm Activities of Cinnamomum Sp. Essential Oil and Cinnamaldehyde: Antimicrobial Activities |
| title_sort | antibacterial and antibiofilm activities of cinnamomum sp essential oil and cinnamaldehyde antimicrobial activities |
| url | http://dx.doi.org/10.1155/2018/7405736 |
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