NCOA5 induces sorafenib resistance in hepatocellular carcinoma by inhibiting ferroptosis

Abstract NCOA5 has been identified as a crucial factor in the progression of hepatocellular carcinoma (HCC). This study investigates the expression of NCOA5 in HCC, revealing its significant overexpression in tumor tissues compared to healthy liver tissues, as evidenced by analysis of the TCGA datas...

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Bibliographic Details
Main Authors: Shuang Gao, Lulu Fan, Huiyan Wang, Anqi Wang, Mengyao Hu, Lei Zhang, Guoping Sun
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02473-1
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