MOG-specific CAR Tregs: a novel approach to treat multiple sclerosis

MOG-specific CAR Tregs: a novel approach to treat multiple sclerosis

Abstract Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system (CNS) with the immune system attacking myelin sheaths leading to neuronal death. While several disease-modifying therapies are available to treat MS, these therapies are not universally effective and do no...

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Main Authors: Jihane Frikeche, Marion David, Xavier Mouska, Damien Treguer, Yue Cui, Sandrine Rouquier, Enora Lecorgne, Emma Proics, Papa Babacar Fall, Audrey Lafon, Gregory Lara, Alexandra Menardi, David Fenard, Tobias Abel, Julie Gertner-Dardenne, Maurus de la Rosa, Celine Dumont
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Journal of Neuroinflammation
Subjects:
CAR-Treg
MOG
Multiple sclerosis
Cell therapy
Online Access:https://doi.org/10.1186/s12974-024-03262-w
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https://doi.org/10.1186/s12974-024-03262-w

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