Application of 19F NMR Spectroscopy for Content Determination of Fluorinated Pharmaceuticals

A simple, rapid, and selective quantitative nuclear magnetic resonance spectroscopic method was evaluated for the determination of the content of fluorinated pharmaceuticals. 19F NMR spectra were either obtained in dimethylsulfoxide-d6 or aqueous buffer, using trifluoroacetic acid as internal standa...

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Bibliographic Details
Main Authors: Alex O. Okaru, Tobias S. Brunner, Svenja M. Ackermann, Thomas Kuballa, Stephan G. Walch, Matthias Kohl-Himmelseher, Dirk W. Lachenmeier
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2017/9206297
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