Interaction between the assembly of the ribosomal subunits: Disruption of 40S ribosomal assembly causes accumulation of extra-ribosomal 60S ribosomal protein uL18/L5.

Interaction between the assembly of the ribosomal subunits: Disruption of 40S ribosomal assembly causes accumulation of extra-ribosomal 60S ribosomal protein uL18/L5.

Inhibition of the synthesis of an essential ribosomal protein (r-protein) abrogates the assembly of its cognate subunit, while assembly of the other subunit continues. Ribosomal components that are not stably incorporated into ribosomal particles due to the disrupted assembly are rapidly degraded. T...

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Bibliographic Details
Main Authors: Nusrat Rahman, Md Shamsuzzaman, Lasse Lindahl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0222479/1/pone.0222479.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210221%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210221T071329Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=1e6458b83c3eb84aef5bbdea7b0912b31b027af78ff45b41b44610b7decfb3a93f50cdb9fc534387d4f221b730981abc1fc715a8cbbe6ee06d678040bbd4db9a717aee79a02c8734b901aecaf6c5343973acaf0de2965c7219e9bc04918293d4a2f2d88eaccd8e5cea0f18dfb2f8e40ee724a66480163a2659a9ed8a5977a9ad54ae5fe47ecf34553f9f5278d7c241d75456191c0e545663742b4c54a329f9b93effc698ed7cc9e5bbffb3b09b3a36f0fe8c3fb5ec7c140d1621e8594141276cc688536647c1ee56b7b658aa05dd2f5a3994e9e4f0aa58086884ae9d8f54df98ad4615555982450a9d025bdae0f74f413c7b9a392ac89bf66bab1f4b6c97b23e
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