Delirium as a mediating factor in the survival benefits of dexmedetomidine in acute brain injury management

Delirium as a mediating factor in the survival benefits of dexmedetomidine in acute brain injury management

Abstract Acute brain injury (ABI) is a leading cause of ICU admission and mortality. Effective sedation is essential for preventing secondary brain injury, and dexmedetomidine has emerged as a potential neuroprotective agent. We conducted a retrospective analysis using the MIMIC-IV v3.1 database, in...

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Bibliographic Details
Main Authors: Juan Wang, Jia-qing Sun, Yue Lu, Qi-lin Yang, Peng-lai Zhao, Chun-Hua Hang, Wei Li
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Dexmedetomidine
Acute brain injury
Delirium
ICU
Mortality.
Online Access:https://doi.org/10.1038/s41598-025-14180-z
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