The Efficacy of Pulsed Electromagnetic Fields on Pain, Stiffness, and Physical Function in Osteoarthritis: A Systematic Review and Meta-Analysis
Background. Although there are many pharmacological interventions for adults with osteoarthritis (OA) who do not meet the indications for surgery, side effects and adverse effects cannot be ignored. Physical interventions are known for their effectiveness and safety, and pulsed electromagnetic field...
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
|
| Series: | Pain Research and Management |
| Online Access: | http://dx.doi.org/10.1155/2022/9939891 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832563450484621312 |
|---|---|
| author | Jie Tong Zhengyu Chen Guanghua Sun Jun Zhou Ye Zeng Peirui Zhong Chengyuan Deng Xiaocui Chen Liu Liu Shiyong Wang Jiaqian Chen Ying Liao |
| author_facet | Jie Tong Zhengyu Chen Guanghua Sun Jun Zhou Ye Zeng Peirui Zhong Chengyuan Deng Xiaocui Chen Liu Liu Shiyong Wang Jiaqian Chen Ying Liao |
| author_sort | Jie Tong |
| collection | DOAJ |
| description | Background. Although there are many pharmacological interventions for adults with osteoarthritis (OA) who do not meet the indications for surgery, side effects and adverse effects cannot be ignored. Physical interventions are known for their effectiveness and safety, and pulsed electromagnetic fields (PEMFs) have already been applied to skeletal diseases such as osteoporosis. Objective. In this systematic review and meta-analysis, we aimed to assess the efficacy of PEMF on the major symptoms of patients with OA compared with efficacy of other interventions. Methods. Randomized controlled trials (RCTs) investigating OA patients treated with PEMF and with pain, stiffness, and physical function impairment since 2009 were included. The Visual Analog Scale (VAS) and Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) scores were used for assessment. All extracted data were analyzed using RevMan V.5.3. Results. Eleven RCTs consisting of 614 patients were enrolled in this meta-analysis, of which 10 trials comprised knee OA and one comprised hand OA. Compared with the control groups, the PEMF treatment yielded a more favorable output. PEMF alleviated pain (standardized mean differences [SMD] = 0.71, 95% confidence interval [CI]: 0.08–1.34, p = 0.03), improved stiffness (SMD = 1.34, 95% CI: 0.45–2.23,p=0.003), and restored physical function (SMD = 1.52, 95% CI: 0.49–2.55,p=0.004). Conclusions. PEMF therapy ameliorates OA symptoms such as pain, stiffness, and physical function in patients compared to other conservative treatments. There is an urgent need to search for different types of OA in multiple locations. |
| format | Article |
| id | doaj-art-b051b2ec1e084a84b7a4ecea57730667 |
| institution | Kabale University |
| issn | 1918-1523 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pain Research and Management |
| spelling | doaj-art-b051b2ec1e084a84b7a4ecea577306672025-02-03T01:20:12ZengWileyPain Research and Management1918-15232022-01-01202210.1155/2022/9939891The Efficacy of Pulsed Electromagnetic Fields on Pain, Stiffness, and Physical Function in Osteoarthritis: A Systematic Review and Meta-AnalysisJie Tong0Zhengyu Chen1Guanghua Sun2Jun Zhou3Ye Zeng4Peirui Zhong5Chengyuan Deng6Xiaocui Chen7Liu Liu8Shiyong Wang9Jiaqian Chen10Ying Liao11Rehabilitation Medicine CenterDepartment of SpineRehabilitation Medicine CenterRehabilitation Medicine CenterRehabilitation Medicine CenterRehabilitation Medicine CenterDepartment of AnatomyDepartment of RehabilitationRehabilitation Medicine CenterRehabilitation Medicine CenterRehabilitation Medicine CenterRehabilitation Medicine CenterBackground. Although there are many pharmacological interventions for adults with osteoarthritis (OA) who do not meet the indications for surgery, side effects and adverse effects cannot be ignored. Physical interventions are known for their effectiveness and safety, and pulsed electromagnetic fields (PEMFs) have already been applied to skeletal diseases such as osteoporosis. Objective. In this systematic review and meta-analysis, we aimed to assess the efficacy of PEMF on the major symptoms of patients with OA compared with efficacy of other interventions. Methods. Randomized controlled trials (RCTs) investigating OA patients treated with PEMF and with pain, stiffness, and physical function impairment since 2009 were included. The Visual Analog Scale (VAS) and Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) scores were used for assessment. All extracted data were analyzed using RevMan V.5.3. Results. Eleven RCTs consisting of 614 patients were enrolled in this meta-analysis, of which 10 trials comprised knee OA and one comprised hand OA. Compared with the control groups, the PEMF treatment yielded a more favorable output. PEMF alleviated pain (standardized mean differences [SMD] = 0.71, 95% confidence interval [CI]: 0.08–1.34, p = 0.03), improved stiffness (SMD = 1.34, 95% CI: 0.45–2.23,p=0.003), and restored physical function (SMD = 1.52, 95% CI: 0.49–2.55,p=0.004). Conclusions. PEMF therapy ameliorates OA symptoms such as pain, stiffness, and physical function in patients compared to other conservative treatments. There is an urgent need to search for different types of OA in multiple locations.http://dx.doi.org/10.1155/2022/9939891 |
| spellingShingle | Jie Tong Zhengyu Chen Guanghua Sun Jun Zhou Ye Zeng Peirui Zhong Chengyuan Deng Xiaocui Chen Liu Liu Shiyong Wang Jiaqian Chen Ying Liao The Efficacy of Pulsed Electromagnetic Fields on Pain, Stiffness, and Physical Function in Osteoarthritis: A Systematic Review and Meta-Analysis Pain Research and Management |
| title | The Efficacy of Pulsed Electromagnetic Fields on Pain, Stiffness, and Physical Function in Osteoarthritis: A Systematic Review and Meta-Analysis |
| title_full | The Efficacy of Pulsed Electromagnetic Fields on Pain, Stiffness, and Physical Function in Osteoarthritis: A Systematic Review and Meta-Analysis |
| title_fullStr | The Efficacy of Pulsed Electromagnetic Fields on Pain, Stiffness, and Physical Function in Osteoarthritis: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | The Efficacy of Pulsed Electromagnetic Fields on Pain, Stiffness, and Physical Function in Osteoarthritis: A Systematic Review and Meta-Analysis |
| title_short | The Efficacy of Pulsed Electromagnetic Fields on Pain, Stiffness, and Physical Function in Osteoarthritis: A Systematic Review and Meta-Analysis |
| title_sort | efficacy of pulsed electromagnetic fields on pain stiffness and physical function in osteoarthritis a systematic review and meta analysis |
| url | http://dx.doi.org/10.1155/2022/9939891 |
| work_keys_str_mv | AT jietong theefficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT zhengyuchen theefficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT guanghuasun theefficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT junzhou theefficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT yezeng theefficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT peiruizhong theefficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT chengyuandeng theefficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT xiaocuichen theefficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT liuliu theefficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT shiyongwang theefficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT jiaqianchen theefficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT yingliao theefficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT jietong efficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT zhengyuchen efficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT guanghuasun efficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT junzhou efficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT yezeng efficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT peiruizhong efficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT chengyuandeng efficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT xiaocuichen efficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT liuliu efficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT shiyongwang efficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT jiaqianchen efficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis AT yingliao efficacyofpulsedelectromagneticfieldsonpainstiffnessandphysicalfunctioninosteoarthritisasystematicreviewandmetaanalysis |