Isolated Langerhans Cell Histiocytosis of the Vulva in a 28-Year-Old Lady: A Report of a Case and Brief Review of the Literature

Langerhans cell histiocytosis (LCH) is a rare, proliferative disorder of Langerhans’ cells. The presentation can vary from single organ involvement to multisystem and disseminated in severe cases, affecting children more than adults. Isolated vulvar involvement of LCH in a 28-year-old woman has rare...

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Main Authors: Maryam Sadat Sadati, Nafiseh Todarbary, Fatemeh Sari Aslani, Maryam Hadibarhaghtalab
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Dermatological Medicine
Online Access:http://dx.doi.org/10.1155/2022/8483008
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author Maryam Sadat Sadati
Nafiseh Todarbary
Fatemeh Sari Aslani
Maryam Hadibarhaghtalab
author_facet Maryam Sadat Sadati
Nafiseh Todarbary
Fatemeh Sari Aslani
Maryam Hadibarhaghtalab
author_sort Maryam Sadat Sadati
collection DOAJ
description Langerhans cell histiocytosis (LCH) is a rare, proliferative disorder of Langerhans’ cells. The presentation can vary from single organ involvement to multisystem and disseminated in severe cases, affecting children more than adults. Isolated vulvar involvement of LCH in a 28-year-old woman has rarely been described and also there are limited data for diagnosis and treatment. Herein, we report the case of a 28-year-old woman with isolated vulvar LCH, misdiagnosed with herpes simplex infection, successfully treated with thalidomide.
format Article
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institution Kabale University
issn 2090-6471
language English
publishDate 2022-01-01
publisher Wiley
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series Case Reports in Dermatological Medicine
spelling doaj-art-b02a79a5a2a24f339731fb3499c2c5f32025-02-03T01:20:08ZengWileyCase Reports in Dermatological Medicine2090-64712022-01-01202210.1155/2022/8483008Isolated Langerhans Cell Histiocytosis of the Vulva in a 28-Year-Old Lady: A Report of a Case and Brief Review of the LiteratureMaryam Sadat Sadati0Nafiseh Todarbary1Fatemeh Sari Aslani2Maryam Hadibarhaghtalab3Molecular Dermatology Research CenterStudent Research CommitteeMolecular Dermatology Research CenterMolecular Dermatology Research CenterLangerhans cell histiocytosis (LCH) is a rare, proliferative disorder of Langerhans’ cells. The presentation can vary from single organ involvement to multisystem and disseminated in severe cases, affecting children more than adults. Isolated vulvar involvement of LCH in a 28-year-old woman has rarely been described and also there are limited data for diagnosis and treatment. Herein, we report the case of a 28-year-old woman with isolated vulvar LCH, misdiagnosed with herpes simplex infection, successfully treated with thalidomide.http://dx.doi.org/10.1155/2022/8483008
spellingShingle Maryam Sadat Sadati
Nafiseh Todarbary
Fatemeh Sari Aslani
Maryam Hadibarhaghtalab
Isolated Langerhans Cell Histiocytosis of the Vulva in a 28-Year-Old Lady: A Report of a Case and Brief Review of the Literature
Case Reports in Dermatological Medicine
title Isolated Langerhans Cell Histiocytosis of the Vulva in a 28-Year-Old Lady: A Report of a Case and Brief Review of the Literature
title_full Isolated Langerhans Cell Histiocytosis of the Vulva in a 28-Year-Old Lady: A Report of a Case and Brief Review of the Literature
title_fullStr Isolated Langerhans Cell Histiocytosis of the Vulva in a 28-Year-Old Lady: A Report of a Case and Brief Review of the Literature
title_full_unstemmed Isolated Langerhans Cell Histiocytosis of the Vulva in a 28-Year-Old Lady: A Report of a Case and Brief Review of the Literature
title_short Isolated Langerhans Cell Histiocytosis of the Vulva in a 28-Year-Old Lady: A Report of a Case and Brief Review of the Literature
title_sort isolated langerhans cell histiocytosis of the vulva in a 28 year old lady a report of a case and brief review of the literature
url http://dx.doi.org/10.1155/2022/8483008
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