Labeling tumor-associated extracellular vesicles with antibody-DNA conjugates for quantitative analysis

Labeling tumor-associated extracellular vesicles with antibody-DNA conjugates for quantitative analysis

IntroductionExtracellular vesicles (EVs) shed from tumor cells into peripheral circulation or other body fluids are promising biomarkers for cancer diagnosis with enormously long circulation. Consequently, precise methods for differentiating normal and tumor-associated EVs (TAEs) are required.Method...

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Bibliographic Details
Main Authors: Xiao Du, Hongxiu Li, Shiyi Shen, Chao Tian, Xiaohuan Cao, Xingang Xu, Nan Xu, Shuling Wang, Qingchang Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Molecular Biosciences
Subjects:
extracellular vesicles
antibody-DNA conjugates
Poisson distribution
proximity ligation technology
tumor diagnosis
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1531108/full
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