Safety and effect of topical neostigmine ophthalmic solution in animal models
Abstract The study aimed to evaluate the safety and effect of various dosages of topical neostigmine ophthalmic solution (TNOS) in animal models and establish a recommended dosage for further studies on myasthenia gravis (MG) diagnosis. A placebo-controlled, sequential ascending dose study was condu...
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| Main Authors: | Chuthamas Ongprakobkul, Supharat Jariyakosol, Supanut Apinyawasisuk, Kasem Rattanapinyopituk, Pajaree Chariyavilaskul, Kornvalee Meesilpavikkai, Yuda Chongpison |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-16328-3 |
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