Effect of 1-(phenyl)-N’-(4-methoxybenzylidene)-9H-pyrido[3,4-b] indole-3-carbohydrazide on in vitro poliovirus replication

Effect of 1-(phenyl)-N’-(4-methoxybenzylidene)-9H-pyrido[3,4-b] indole-3-carbohydrazide on in vitro poliovirus replication

The effect of the alkaloid 1-(phenyl)-N’-(4-methoxybenzylidene)- 9H-pyrido[3,4-b]indole-3-carbohydrazide (PMC) on the poliovirus (PV) replication cycle in Vero cells was assayed by inhibition of the cytopathic effect (CPE) and inhibition of plaque forming units (PFU). Both methodologies suggested th...

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Bibliographic Details
Main Authors: Santos Patricia Regina, Formagio Anelise S. Nazari, Filho Benedito Prado Dias, Nakamura Celso Vataru, Sarragiotto Maria Helena, Ueda-Nakamura Tania
Format: Article
Language:English
Published: Sciendo 2015-03-01
Series:Acta Pharmaceutica
Subjects:
1-(phenyl)-n’-(4-methoxybenzylidene)-9h-pyrido[ 3,4-b]indole-3-carbohydrazide
b-carboline
poliovirus
antiviral activity
Online Access:https://doi.org/10.1515/acph-2015-0004
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https://doi.org/10.1515/acph-2015-0004

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