Sotatercept Use in a Patient with Pulmonary Arterial Hypertension Undergoing Lung Transplantation
Pulmonary arterial hypertension (PAH) is one of the common indications for lung transplantation. Sotatercept is a new medication with a novel mechanism of action and was recently approved for the treatment of PAH. Sotatercept is associated with significant adverse effects including thrombocytopenia...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-05-01
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| Series: | JHLT Open |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2950133425000084 |
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| _version_ | 1832087412244742144 |
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| author | Justin P. Rosenheck Kashika Goyal Tara Fallah Pamela Burcham Kukbin Choi Matthew Henn Elie Homsy Scott Visovatti Veronica Franco |
| author_facet | Justin P. Rosenheck Kashika Goyal Tara Fallah Pamela Burcham Kukbin Choi Matthew Henn Elie Homsy Scott Visovatti Veronica Franco |
| author_sort | Justin P. Rosenheck |
| collection | DOAJ |
| description | Pulmonary arterial hypertension (PAH) is one of the common indications for lung transplantation. Sotatercept is a new medication with a novel mechanism of action and was recently approved for the treatment of PAH. Sotatercept is associated with significant adverse effects including thrombocytopenia and erythrocytosis which can impact outcomes of lung transplantation. This is the first described case of a patient undergoing lung transplantation while receiving sotatercept for PAH. |
| format | Article |
| id | doaj-art-b01338c2f11843fcad28a0ae4a334ffd |
| institution | Kabale University |
| issn | 2950-1334 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JHLT Open |
| spelling | doaj-art-b01338c2f11843fcad28a0ae4a334ffd2025-02-06T05:13:09ZengElsevierJHLT Open2950-13342025-05-018100213Sotatercept Use in a Patient with Pulmonary Arterial Hypertension Undergoing Lung TransplantationJustin P. Rosenheck0Kashika Goyal1Tara Fallah2Pamela Burcham3Kukbin Choi4Matthew Henn5Elie Homsy6Scott Visovatti7Veronica Franco8Ohio State University, Department of Internal Medicine, Division of Pulmonary Critical Care and Sleep Medicine, Davis Heart and Lung Institute, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH; Reprint requests: Justin P. Rosenheck, Ohio State University, Department of Internal Medicine, Division of Pulmonary Critical Care and Sleep Medicine, 241 W. 11th Avenue, 5th Floor, Suite 5055L, Columbus, OH 43201.Ohio State University, Department of Internal Medicine, Division of Pulmonary Critical Care and Sleep Medicine, Davis Heart and Lung Institute, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OHOhio State University, College of Pharmacy, 217 Lloyd M. Parks Hall, 500 West 12th Ave, Columbus OH 43210Ohio State University, College of Pharmacy, 217 Lloyd M. Parks Hall, 500 West 12th Ave, Columbus OH 43210Ohio State University, Department of Surgery, Division of Cardiac Surgery, 410 W. 10th Ave, Columbus OH 43210Ohio State University, Department of Surgery, Division of Cardiac Surgery, 410 W. 10th Ave, Columbus OH 43210Ohio State University, Department of Internal Medicine, Division of Pulmonary Critical Care and Sleep Medicine, Davis Heart and Lung Institute, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OHOhio State University, Department of Internal Medicine, Division of Cardiovascular Medicine, 452 W 10th Ave, Columbus, OH 43210Ohio State University, Department of Internal Medicine, Division of Cardiovascular Medicine, 452 W 10th Ave, Columbus, OH 43210Pulmonary arterial hypertension (PAH) is one of the common indications for lung transplantation. Sotatercept is a new medication with a novel mechanism of action and was recently approved for the treatment of PAH. Sotatercept is associated with significant adverse effects including thrombocytopenia and erythrocytosis which can impact outcomes of lung transplantation. This is the first described case of a patient undergoing lung transplantation while receiving sotatercept for PAH.http://www.sciencedirect.com/science/article/pii/S2950133425000084Pulmonary Arterial HypertensionPAHGroup 1Lung TransplantSotatercept |
| spellingShingle | Justin P. Rosenheck Kashika Goyal Tara Fallah Pamela Burcham Kukbin Choi Matthew Henn Elie Homsy Scott Visovatti Veronica Franco Sotatercept Use in a Patient with Pulmonary Arterial Hypertension Undergoing Lung Transplantation JHLT Open Pulmonary Arterial Hypertension PAH Group 1 Lung Transplant Sotatercept |
| title | Sotatercept Use in a Patient with Pulmonary Arterial Hypertension Undergoing Lung Transplantation |
| title_full | Sotatercept Use in a Patient with Pulmonary Arterial Hypertension Undergoing Lung Transplantation |
| title_fullStr | Sotatercept Use in a Patient with Pulmonary Arterial Hypertension Undergoing Lung Transplantation |
| title_full_unstemmed | Sotatercept Use in a Patient with Pulmonary Arterial Hypertension Undergoing Lung Transplantation |
| title_short | Sotatercept Use in a Patient with Pulmonary Arterial Hypertension Undergoing Lung Transplantation |
| title_sort | sotatercept use in a patient with pulmonary arterial hypertension undergoing lung transplantation |
| topic | Pulmonary Arterial Hypertension PAH Group 1 Lung Transplant Sotatercept |
| url | http://www.sciencedirect.com/science/article/pii/S2950133425000084 |
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