Defluorinative functionalization approach led by difluoromethyl anion chemistry

Abstract Organofluorine compounds have greatly benefited the pharmaceutical, agrochemical, and materials sectors. However, they are plagued by concerns associated with Per- and Polyfluoroalkyl Substances. Additionally, the widespread use of the trifluoromethyl group is facing imminent regulatory scr...

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Bibliographic Details
Main Authors: Kensuke Muta, Kazuhiro Okamoto, Hiroki Nakayama, Shuto Wada, Aiichiro Nagaki
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-52842-0
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