Flaviviruses—Induced Neurological Sequelae
Flaviviruses, a group of single-stranded RNA viruses spread by mosquitoes or ticks, include several significant neurotropic viruses, such as West Nile virus (WNV), Japanese encephalitis virus (JEV), tick-borne encephalitis virus (TBEV), and Zika virus (ZIKV). These viruses can cause a range of neuro...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-12-01
|
| Series: | Pathogens |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-0817/14/1/22 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832587772922167296 |
|---|---|
| author | Samantha Gabrielle Cody Awadalkareem Adam Andrei Siniavin Sam S. Kang Tian Wang |
| author_facet | Samantha Gabrielle Cody Awadalkareem Adam Andrei Siniavin Sam S. Kang Tian Wang |
| author_sort | Samantha Gabrielle Cody |
| collection | DOAJ |
| description | Flaviviruses, a group of single-stranded RNA viruses spread by mosquitoes or ticks, include several significant neurotropic viruses, such as West Nile virus (WNV), Japanese encephalitis virus (JEV), tick-borne encephalitis virus (TBEV), and Zika virus (ZIKV). These viruses can cause a range of neurological diseases during acute infection, from mild, flu-like symptoms to severe and fatal encephalitis. A total of 20–50% of patients who recovered from acute flavivirus infections experienced long-term cognitive issues. Here, we discuss these major neurotropic flaviviruses-induced clinical diseases in humans and the recent findings in animal models and provide insights into the underlying disease mechanisms. |
| format | Article |
| id | doaj-art-afcb210bb4f14638a3b4fbcbc191e2e1 |
| institution | Kabale University |
| issn | 2076-0817 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj-art-afcb210bb4f14638a3b4fbcbc191e2e12025-01-24T13:44:38ZengMDPI AGPathogens2076-08172024-12-011412210.3390/pathogens14010022Flaviviruses—Induced Neurological SequelaeSamantha Gabrielle Cody0Awadalkareem Adam1Andrei Siniavin2Sam S. Kang3Tian Wang4Department of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX 77555, USADepartment of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX 77555, USADepartment of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX 77555, USADepartment of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX 77555, USADepartment of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX 77555, USAFlaviviruses, a group of single-stranded RNA viruses spread by mosquitoes or ticks, include several significant neurotropic viruses, such as West Nile virus (WNV), Japanese encephalitis virus (JEV), tick-borne encephalitis virus (TBEV), and Zika virus (ZIKV). These viruses can cause a range of neurological diseases during acute infection, from mild, flu-like symptoms to severe and fatal encephalitis. A total of 20–50% of patients who recovered from acute flavivirus infections experienced long-term cognitive issues. Here, we discuss these major neurotropic flaviviruses-induced clinical diseases in humans and the recent findings in animal models and provide insights into the underlying disease mechanisms.https://www.mdpi.com/2076-0817/14/1/22flavivirusneurotropicneurological sequelaeanimal models |
| spellingShingle | Samantha Gabrielle Cody Awadalkareem Adam Andrei Siniavin Sam S. Kang Tian Wang Flaviviruses—Induced Neurological Sequelae Pathogens flavivirus neurotropic neurological sequelae animal models |
| title | Flaviviruses—Induced Neurological Sequelae |
| title_full | Flaviviruses—Induced Neurological Sequelae |
| title_fullStr | Flaviviruses—Induced Neurological Sequelae |
| title_full_unstemmed | Flaviviruses—Induced Neurological Sequelae |
| title_short | Flaviviruses—Induced Neurological Sequelae |
| title_sort | flaviviruses induced neurological sequelae |
| topic | flavivirus neurotropic neurological sequelae animal models |
| url | https://www.mdpi.com/2076-0817/14/1/22 |
| work_keys_str_mv | AT samanthagabriellecody flavivirusesinducedneurologicalsequelae AT awadalkareemadam flavivirusesinducedneurologicalsequelae AT andreisiniavin flavivirusesinducedneurologicalsequelae AT samskang flavivirusesinducedneurologicalsequelae AT tianwang flavivirusesinducedneurologicalsequelae |