Bisphenol A exposure enhances proliferation and tumorigenesis of papillary thyroid carcinoma through ROS generation and activation of NOX4 signaling pathways

Bisphenol A exposure enhances proliferation and tumorigenesis of papillary thyroid carcinoma through ROS generation and activation of NOX4 signaling pathways

As a prevalent industrial material and component of consumer products, bisphenol A (BPA) is linked to hormone homeostasis disruption and potential carcinogenicity. However, the precise mechanisms through which BPA contributes to thyroid carcinogenesis, especially in papillary thyroid carcinoma (PTC)...

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Bibliographic Details
Main Authors: Yi Wang, Xuling Su, Qianqian Wang, Likun Zhang, Yaling Yu, Yiwei Zhao, Zhiyan Liu
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Ecotoxicology and Environmental Safety
Subjects:
BPA
papillary thyroid carcinoma
ROS
Tumorigenesis
NOX4
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325002829
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