TNFα activation of the PLEKHA5-FCRLA axis disturbs lipid metabolism, leading to the progression of cutaneous malignant melanoma

TNFα activation of the PLEKHA5-FCRLA axis disturbs lipid metabolism, leading to the progression of cutaneous malignant melanoma

Abstract Background Cutaneous malignant melanoma (CMM) ranks among the deadliest forms of cancer. Abnormalities in lipid metabolism may have a connection with the risk of CMM progression. Methods Lipid metabolism-related genes were selected in MSigDB. A lipid metabolism-related predictive model was...

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Bibliographic Details
Main Authors: Kexin Yan, Wei Zhang, Wenqi Chu, Jinliang Qi, Hao Song, Xiulian Xu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Lipids in Health and Disease
Subjects:
Lipid metabolism
Cutaneous malignant melanoma
Oncogene
Risk model
Online Access:https://doi.org/10.1186/s12944-025-02597-4
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https://doi.org/10.1186/s12944-025-02597-4

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