Differential impact of eicosapentaenoic acid and docosahexaenoic acid in an animal model of Alzheimer’s disease

Differential impact of eicosapentaenoic acid and docosahexaenoic acid in an animal model of Alzheimer’s disease

Dietary supplementation with n-3 polyunsaturated fatty acids improves cognitive performance in several animal models of Alzheimer's disease (AD), an effect often associated with reduced amyloid-beta and/or tau pathologies. However, it remains unclear to what extent eicosapentaenoic (EPA) provid...

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Bibliographic Details
Main Authors: Méryl-Farelle Oye Mintsa Mi-mba, Meryem Lebbadi, Waël Alata, Carl Julien, Vincent Emond, Cyntia Tremblay, Samuel Fortin, Colin J. Barrow, Jean-François Bilodeau, Frédéric Calon
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Lipid Research
Subjects:
3xTg-AD mice
Alzheimer’s disease
eicosapentaenoic acid
docosahexaenoic acid
n-3 polyunsaturated fatty acids
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227524001871
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