Association between extracellular DNA levels, markers of inflammation and left ventricular mass index in children with chronic kidney disease

Association between extracellular DNA levels, markers of inflammation and left ventricular mass index in children with chronic kidney disease

Abstract Chronic kidney disease (CKD) is associated with chronic low-grade inflammation, but the primary factors triggering this inflammation remain unclear. Extracellular or cell-free DNA (exDNA) originates from virtually all tissues, being released during cell death, and stimulates the innate immu...

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Bibliographic Details
Main Authors: Ylva Tranæus Lindblad, Ľubomíra Tóthová, Peter Celec, Karolina Kublickiene, Peter Bárány, Milan Chromek
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Chronic kidney disease
Extracellular DNA
Cell-free DNA
Cardiovascular disease
Kidney transplantation
Sterile inflammation
Online Access:https://doi.org/10.1038/s41598-025-86857-4
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https://doi.org/10.1038/s41598-025-86857-4

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