Resveratrol attenuates the CoCl2-induced hypoxia damage by regulation of lysine β-hydroxybutyrylation in PC12 cells

Resveratrol attenuates the CoCl2-induced hypoxia damage by regulation of lysine β-hydroxybutyrylation in PC12 cells

Abstract Background Stroke is a cerebrovascular disease that is the main cause of death and disability worldwide. Hypoxia is a major factor that causes neuronal damage and even cellular death. However, the mechanism and therapeutic drugs for hypoxia are not completely understood. Methods In this stu...

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Bibliographic Details
Main Authors: Yamei Wang, Jian Zhao, Liang Sun, Dingding Xu, Xiaoming Wei, Jia Li, Zihan Mo, Nian Xia, Junge Zhou, Yuan Yao, Qiao Hu, Qingqing Zhou
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Neurology
Subjects:
Resveratrol
CoCl2
Hypoxia
Lysine β-hydroxybutyrylation
PC12 cells
Reactive oxygen species
Online Access:https://doi.org/10.1186/s12883-025-04171-y
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https://doi.org/10.1186/s12883-025-04171-y

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