Principles of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in disease

Abstract The endothelium is the orchestral conductor of blood vessel function. Pathological blood vessel formation (a process termed pathological angiogenesis) or the inability of endothelial cells (ECs) to perform their physiological function (a condition known as EC dysfunction) are defining featu...

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Bibliographic Details
Main Authors: Jermaine Goveia, Peter Stapor, Peter Carmeliet
Format: Article
Language:English
Published: Springer Nature 2014-07-01
Series:EMBO Molecular Medicine
Subjects:
Online Access:https://doi.org/10.15252/emmm.201404156
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