Dual‐Gating Strategy: Ultrasound Activation of TRPV2 Channels and Borate‐Glass‐Induced Calcium Overload for Tumor Suppression

Dual‐Gating Strategy: Ultrasound Activation of TRPV2 Channels and Borate‐Glass‐Induced Calcium Overload for Tumor Suppression

Abstract Effective and precise treatment of breast cancer, particularly with bone metastasis, remains a significant challenge. Here, a dual‐gating strategy combining locally delivered borate glass (BG) and ultrasound (US) is developed for the precise and effective inhibition of breast cancer by targ...

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Bibliographic Details
Main Authors: Haihong Zhu, Liping Ouyang, Yangguang Huang, Ji Tan, Chunyu Liu, Qian Wang, Rongkun Huang, Wing Tak Wong, Xuanyong Liu, Haobo Pan, Yun Liao
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
borate glass
calcium overload
precise breast cancer treatment
TRPV2
ultrasound
Online Access:https://doi.org/10.1002/advs.202414676
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https://doi.org/10.1002/advs.202414676

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