Ketomimetic nutrients remodel the glycocalyx and trigger a metabolic defense in breast cancer cells

Ketomimetic nutrients remodel the glycocalyx and trigger a metabolic defense in breast cancer cells

Abstract Background While the triggers for the metastatic transformation of breast cancer (BC) cells remain unknown, recent evidence suggests that intrinsic cellular metabolism could be a crucial driver of migratory disposition and chemoresistance. Aiming to decipher the molecular mechanisms involve...

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Bibliographic Details
Main Authors: Mohini Kamra, Yuan-I Chen, Paula C. Delgado, Erin H. Seeley, Stephanie K. Seidlits, Hsin-Chih Yeh, Amy Brock, Sapun H. Parekh
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Cancer & Metabolism
Subjects:
Ketomimetic
Glycocalyx engineering
Hypersialylation
Lipid metabolism
Breast cancer metabolism
Ketogenic diet
Online Access:https://doi.org/10.1186/s40170-025-00385-3
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https://doi.org/10.1186/s40170-025-00385-3

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