High p16INK4A expression in glioblastoma is associated with senescence phenotype and better prognosis

High p16INK4A expression in glioblastoma is associated with senescence phenotype and better prognosis

Glioblastoma, isocitrate dehydrogenase (IDH)-wildtype (GBM), is the most malignant brain tumor in adults, with limited therapeutic intervention. Previous studies have identified a few prognostic markers for GBM, including the methylation status of O6-methylguanine-DNA methyltransferase (MGMT) promot...

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Bibliographic Details
Main Authors: Soon Sang Park, Tae Hoon Roh, Yoshiaki Tanaka, Young Hwa Kim, So Hyun Park, Tae-Gyu Kim, So Yeong Eom, Tae Jun Park, In-Hyun Park, Se-Hyuk Kim, Jang-Hee Kim
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Glioblastoma
GBM IDH-wildtype
Senescence
Senescent tumor cells
CCL13
Online Access:http://www.sciencedirect.com/science/article/pii/S147655862400157X
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