Evaluation of intestinal biopsy tissue preservation methods to facilitate large-scale mucosal microbiota researchResearch in context

Evaluation of intestinal biopsy tissue preservation methods to facilitate large-scale mucosal microbiota researchResearch in context

Summary: Background: Large-scale multicentre studies are needed to understand complex relationships between the gut microbiota, health and disease. Interrogating the mucosal microbiota may identify important biology not captured by stool analysis. Gold standard tissue cryopreservation (‘flash freez...

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Main Authors: Nicola J. Wyatt, Hannah Watson, Gregory R. Young, Mary Doona, Ned Tilling, Dean Allerton, Andrea C. Masi, Tariq Ahmad, Jennifer A. Doyle, Katherine Frith, Ailsa Hart, Victoria Hildreth, Peter M. Irving, Claire Jones, Nicholas A. Kennedy, Sarah Lawrence, Charlie W. Lees, Robert Lees, Trevor Liddle, James O. Lindsay, Julian R. Marchesi, Miles Parkes, Nick Powell, Natalie J. Prescott, Tim Raine, Jack Satsangi, Kevin Whelan, Ruth Wood, Andrew King, Luke Jostins-Dean, R. Alexander Speight, Naomi McGregor, Christopher J. Stewart, Christopher A. Lamb
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:EBioMedicine
Subjects:
Inflammatory bowel disease
Precision medicine
Gut microbiome
Tissue microbiome
Tissue preservative reagents
Formalin fixed paraffin embedded
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424005863
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