Population Pharmacokinetic Modeling of the Oral Calcitonin Gene‐Related Peptide Receptor Antagonist Rimegepant in Adults

Population Pharmacokinetic Modeling of the Oral Calcitonin Gene‐Related Peptide Receptor Antagonist Rimegepant in Adults

ABSTRACT Rimegepant is a small‐molecule calcitonin gene‐related peptide receptor antagonist approved for acute and preventive migraine treatment in adults, administered as an orally disintegrating tablet (ODT). A population pharmacokinetic analysis was performed to describe rimegepant's plasma...

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Bibliographic Details
Main Authors: Craig M. Comisar, Jim H. Hughes, Jose Francis, Yorinao Chinda, Yamato Sano, Chieko Muto, Christine Neumar, Rajinder Bhardwaj, Richard Bertz, Jing Liu
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Subjects:
calcitonin gene‐related peptide receptor antagonists
migraine
population pharmacokinetic modeling
rimegepant
Online Access:https://doi.org/10.1002/psp4.70051
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https://doi.org/10.1002/psp4.70051

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