Clinical Outcomes of Aberration-Free All Surface Laser Ablation (ASLA) vs. Aberration-Free ASLA Assisted by Smart Pulse Technology in High Myopia: A One-Year Follow-Up Study

Purpose. To compare the clinical outcomes of aberration-free all surface laser ablation (ASLA) with and without the use of smart pulse technology (SPT) in high myopia. Methods. This study retrospectively analyzed 138 eyes (138 patients, only the right eye was selected) treated for high myopia (spher...

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Main Authors: XiaoHao Du, Jia Zhang, Meng Su, WenJia Cao, Shuang Zeng, QinMei Wang, Ioannis M. Aslanides, ShiHao Chen
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2021/2588765
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author XiaoHao Du
Jia Zhang
Meng Su
WenJia Cao
Shuang Zeng
QinMei Wang
Ioannis M. Aslanides
ShiHao Chen
author_facet XiaoHao Du
Jia Zhang
Meng Su
WenJia Cao
Shuang Zeng
QinMei Wang
Ioannis M. Aslanides
ShiHao Chen
author_sort XiaoHao Du
collection DOAJ
description Purpose. To compare the clinical outcomes of aberration-free all surface laser ablation (ASLA) with and without the use of smart pulse technology (SPT) in high myopia. Methods. This study retrospectively analyzed 138 eyes (138 patients, only the right eye was selected) treated for high myopia (spherical equivalent ≥−6.00 diopters) using aberration-free ASLA (non-SPT group; 85 eyes) and aberration-free ASLA assisted by SPT (SPT group; 53 eyes). Examinations such as visual acuity, refraction, and haze were performed before the 12-month follow-up. Corneal epithelial healing time was assessed in the first postoperative day. Visual acuity and refraction examination were performed at 7 days and 1, 3, 6, and 12 months postoperatively. Corneal haze was evaluated in 1, 3, 6, and 12 months. Safety, efficacy, and corneal wavefront aberrations were assessed 12 months after the treatment. Results. At 12 months postoperatively, 60% versus 40% of eyes achieved 20/16 Snellen lines or better, and 92% versus 82% of eyes achieved 20/20 Snellen lines or better visual acuity in the SPT and the non-SPT groups, respectively. The average postoperative epithelial healing time was 3.75 ± 1.00 days in the SPT group and 3.73 ± 1.30 days in the non-SPT group (P≥0.05). The safety and the efficacy index of the SPT group were better than those of the non-SPT group in the follow-ups. The attempted spherical equivalent before the surgery and the achieved spherical equivalent at 12 months were comparable between the two groups. Regarding the aberrations, the results of Coma 90° in the SPT group were better than those in the non-SPT group (P≤0.05), but the increase of RMS HOAs (root mean square higher order aberrations), Coma 0°, and spherical aberration postoperatively had no statistical difference between the two groups (P≥0.05). Conclusions: Both aberration-free ASLA with and without SPT showed favorable safety, effectiveness, and predictability within 12 months for high myopia. And, ASLA using SPT might have potential advantages in the long-term visual quality.
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spelling doaj-art-ade8190ee88a43489ea7a6ed3d96cab42025-02-03T01:27:05ZengWileyJournal of Ophthalmology2090-004X2090-00582021-01-01202110.1155/2021/25887652588765Clinical Outcomes of Aberration-Free All Surface Laser Ablation (ASLA) vs. Aberration-Free ASLA Assisted by Smart Pulse Technology in High Myopia: A One-Year Follow-Up StudyXiaoHao Du0Jia Zhang1Meng Su2WenJia Cao3Shuang Zeng4QinMei Wang5Ioannis M. Aslanides6ShiHao Chen7School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, ChinaSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, ChinaSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, ChinaSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, ChinaSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, ChinaSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, ChinaEmmetropia Mediterranean Eye Institute, Heraklion, Crete, GreeceSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, ChinaPurpose. To compare the clinical outcomes of aberration-free all surface laser ablation (ASLA) with and without the use of smart pulse technology (SPT) in high myopia. Methods. This study retrospectively analyzed 138 eyes (138 patients, only the right eye was selected) treated for high myopia (spherical equivalent ≥−6.00 diopters) using aberration-free ASLA (non-SPT group; 85 eyes) and aberration-free ASLA assisted by SPT (SPT group; 53 eyes). Examinations such as visual acuity, refraction, and haze were performed before the 12-month follow-up. Corneal epithelial healing time was assessed in the first postoperative day. Visual acuity and refraction examination were performed at 7 days and 1, 3, 6, and 12 months postoperatively. Corneal haze was evaluated in 1, 3, 6, and 12 months. Safety, efficacy, and corneal wavefront aberrations were assessed 12 months after the treatment. Results. At 12 months postoperatively, 60% versus 40% of eyes achieved 20/16 Snellen lines or better, and 92% versus 82% of eyes achieved 20/20 Snellen lines or better visual acuity in the SPT and the non-SPT groups, respectively. The average postoperative epithelial healing time was 3.75 ± 1.00 days in the SPT group and 3.73 ± 1.30 days in the non-SPT group (P≥0.05). The safety and the efficacy index of the SPT group were better than those of the non-SPT group in the follow-ups. The attempted spherical equivalent before the surgery and the achieved spherical equivalent at 12 months were comparable between the two groups. Regarding the aberrations, the results of Coma 90° in the SPT group were better than those in the non-SPT group (P≤0.05), but the increase of RMS HOAs (root mean square higher order aberrations), Coma 0°, and spherical aberration postoperatively had no statistical difference between the two groups (P≥0.05). Conclusions: Both aberration-free ASLA with and without SPT showed favorable safety, effectiveness, and predictability within 12 months for high myopia. And, ASLA using SPT might have potential advantages in the long-term visual quality.http://dx.doi.org/10.1155/2021/2588765
spellingShingle XiaoHao Du
Jia Zhang
Meng Su
WenJia Cao
Shuang Zeng
QinMei Wang
Ioannis M. Aslanides
ShiHao Chen
Clinical Outcomes of Aberration-Free All Surface Laser Ablation (ASLA) vs. Aberration-Free ASLA Assisted by Smart Pulse Technology in High Myopia: A One-Year Follow-Up Study
Journal of Ophthalmology
title Clinical Outcomes of Aberration-Free All Surface Laser Ablation (ASLA) vs. Aberration-Free ASLA Assisted by Smart Pulse Technology in High Myopia: A One-Year Follow-Up Study
title_full Clinical Outcomes of Aberration-Free All Surface Laser Ablation (ASLA) vs. Aberration-Free ASLA Assisted by Smart Pulse Technology in High Myopia: A One-Year Follow-Up Study
title_fullStr Clinical Outcomes of Aberration-Free All Surface Laser Ablation (ASLA) vs. Aberration-Free ASLA Assisted by Smart Pulse Technology in High Myopia: A One-Year Follow-Up Study
title_full_unstemmed Clinical Outcomes of Aberration-Free All Surface Laser Ablation (ASLA) vs. Aberration-Free ASLA Assisted by Smart Pulse Technology in High Myopia: A One-Year Follow-Up Study
title_short Clinical Outcomes of Aberration-Free All Surface Laser Ablation (ASLA) vs. Aberration-Free ASLA Assisted by Smart Pulse Technology in High Myopia: A One-Year Follow-Up Study
title_sort clinical outcomes of aberration free all surface laser ablation asla vs aberration free asla assisted by smart pulse technology in high myopia a one year follow up study
url http://dx.doi.org/10.1155/2021/2588765
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