The Efficacy of Endoscopic Submucosal Dissection of Type I Gastric Carcinoid Tumors Compared with Conventional Endoscopic Mucosal Resection
Background and Aims. Conventional endoscopic submucosal resection (EMR) of carcinoid tumors often involves the resection margin, which necessitates further intervention. Endoscopic submucosal dissection (ESD) is widely accepted for removing carcinoid tumors. We aimed to evaluate the clinical usefuln...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2014/253860 |
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| author | Hyung Hun Kim Gwang Ha Kim Ji Hyun Kim Myung-Gyu Choi Geun Am Song Sung Eun Kim |
| author_facet | Hyung Hun Kim Gwang Ha Kim Ji Hyun Kim Myung-Gyu Choi Geun Am Song Sung Eun Kim |
| author_sort | Hyung Hun Kim |
| collection | DOAJ |
| description | Background and Aims. Conventional endoscopic submucosal resection (EMR) of carcinoid tumors often involves the resection margin, which necessitates further intervention. Endoscopic submucosal dissection (ESD) is widely accepted for removing carcinoid tumors. We aimed to evaluate the clinical usefulness of ESD with that of EMR for resection of type I gastric carcinoid tumors. Patients and Methods. The study enrolled 62 patients (37 males, 25 females; median age, 50 years; range, 40–68 years) who were treated with EMR or ESD at three hospitals; the study group had 87 type I gastric carcinoid tumors with an estimated size of ≤10 mm. The complete resection rate and the complications associated with these two procedures were analyzed. Results. The overall ESD complete resection rate was higher than that of the EMR rate (94.9% versus 83.3%, P value = 0.174). A statistically lower vertical margin involvement rate was achieved when ESD was performed compared to when EMR was performed (2.6% versus 16.7%, P value = 0.038). The complication rate was not significantly different between the two groups. Conclusions. ESD showed a higher complete resection rate, particularly for the vertical margin, with a similar complication rate. We mildly recommend ESD rather than EMR for removing type I gastric carcinoid tumors. |
| format | Article |
| id | doaj-art-adbfb4148fd14cc48c4cfdb8aff1fdff |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-adbfb4148fd14cc48c4cfdb8aff1fdff2025-02-03T01:01:09ZengWileyGastroenterology Research and Practice1687-61211687-630X2014-01-01201410.1155/2014/253860253860The Efficacy of Endoscopic Submucosal Dissection of Type I Gastric Carcinoid Tumors Compared with Conventional Endoscopic Mucosal ResectionHyung Hun Kim0Gwang Ha Kim1Ji Hyun Kim2Myung-Gyu Choi3Geun Am Song4Sung Eun Kim5Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul 137-701, Republic of KoreaDepartment of Internal Medicine, Pusan National University, School of Medicine, Busan 614-735, Republic of KoreaDepartment of Internal Medicine, Inje University College of Medicine, Busan Paik Hospital, Gaegeum-dong, Busanjin-Gu, Busan 602-739, Republic of KoreaDepartment of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul 137-701, Republic of KoreaDepartment of Internal Medicine, Pusan National University, School of Medicine, Busan 614-735, Republic of KoreaDepartment of Internal Medicine, Kosin University College of Medicine, Busan 602-702, Republic of KoreaBackground and Aims. Conventional endoscopic submucosal resection (EMR) of carcinoid tumors often involves the resection margin, which necessitates further intervention. Endoscopic submucosal dissection (ESD) is widely accepted for removing carcinoid tumors. We aimed to evaluate the clinical usefulness of ESD with that of EMR for resection of type I gastric carcinoid tumors. Patients and Methods. The study enrolled 62 patients (37 males, 25 females; median age, 50 years; range, 40–68 years) who were treated with EMR or ESD at three hospitals; the study group had 87 type I gastric carcinoid tumors with an estimated size of ≤10 mm. The complete resection rate and the complications associated with these two procedures were analyzed. Results. The overall ESD complete resection rate was higher than that of the EMR rate (94.9% versus 83.3%, P value = 0.174). A statistically lower vertical margin involvement rate was achieved when ESD was performed compared to when EMR was performed (2.6% versus 16.7%, P value = 0.038). The complication rate was not significantly different between the two groups. Conclusions. ESD showed a higher complete resection rate, particularly for the vertical margin, with a similar complication rate. We mildly recommend ESD rather than EMR for removing type I gastric carcinoid tumors.http://dx.doi.org/10.1155/2014/253860 |
| spellingShingle | Hyung Hun Kim Gwang Ha Kim Ji Hyun Kim Myung-Gyu Choi Geun Am Song Sung Eun Kim The Efficacy of Endoscopic Submucosal Dissection of Type I Gastric Carcinoid Tumors Compared with Conventional Endoscopic Mucosal Resection Gastroenterology Research and Practice |
| title | The Efficacy of Endoscopic Submucosal Dissection of Type I Gastric Carcinoid Tumors Compared with Conventional Endoscopic Mucosal Resection |
| title_full | The Efficacy of Endoscopic Submucosal Dissection of Type I Gastric Carcinoid Tumors Compared with Conventional Endoscopic Mucosal Resection |
| title_fullStr | The Efficacy of Endoscopic Submucosal Dissection of Type I Gastric Carcinoid Tumors Compared with Conventional Endoscopic Mucosal Resection |
| title_full_unstemmed | The Efficacy of Endoscopic Submucosal Dissection of Type I Gastric Carcinoid Tumors Compared with Conventional Endoscopic Mucosal Resection |
| title_short | The Efficacy of Endoscopic Submucosal Dissection of Type I Gastric Carcinoid Tumors Compared with Conventional Endoscopic Mucosal Resection |
| title_sort | efficacy of endoscopic submucosal dissection of type i gastric carcinoid tumors compared with conventional endoscopic mucosal resection |
| url | http://dx.doi.org/10.1155/2014/253860 |
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