PROTAC<sup>®</sup> technology and potential for its application in infection control

Objectives. To describe the pharmaceutical technology of controlled degradation of protein molecules (PROTAC®, Proteolysis Targeting Chimera), approaches to the design of the PROTAC® molecule, methods of ligand and linker selection and synthesis, as well as the application of this technology in deal...

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Bibliographic Details
Main Authors: M. A. Zakharova, M. V. Chudinov
Format: Article
Language:Russian
Published: MIREA - Russian Technological University 2024-07-01
Series:Тонкие химические технологии
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Online Access:https://www.finechem-mirea.ru/jour/article/view/2086
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