Immunoinformatics Predictions on Variable <i>Mycobacterium tuberculosis</i> Lineage 6 T Cell Epitopes and HLA Interactions in West Africa

Immunoinformatics Predictions on Variable <i>Mycobacterium tuberculosis</i> Lineage 6 T Cell Epitopes and HLA Interactions in West Africa

Tuberculosis (TB), caused by <i>Mycobacterium tuberculosis</i> (Mtb), remains a global health challenge. The human-adapted TB-causing bacteria are distributed into ten lineages with distinct global distributions and clinical outcomes. Mtb lineages 4 (L4) and L6 are good prototypes of the...

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Bibliographic Details
Main Authors: Marta L. Silva, Nuno S. Osório, Margarida Saraiva
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Microorganisms
Subjects:
<i>Mycobacterium tuberculosis</i>
phylogeographic lineages
antigens
HLA binding affinity
host–pathogen interactions
co-evolution
Online Access:https://www.mdpi.com/2076-2607/13/5/1032
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