Detection of Quadruplex DNA by Gold Nanoparticles

Gold nanoparticles have been used as a probe to detect low (<10 ppb) concentrations of quadruplex DNA. These nanoparticles display a tendency to form aggregates in the presence of certain quadruplex forms, as observed via enhanced plasmon resonance light scattering (PRLS) signals. These nanoparti...

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Bibliographic Details
Main Authors: Heather F. Crouse, Alex Doudt, Cassie Zerbe, Swarna Basu
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2012/327603
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